paramus-chemistry

What This Skill Does

The paramus-chemistry skill transforms your OpenClaw AI agent into a sophisticated scientific laboratory assistant. It provides direct, programmatic access to the Paramus computational chemistry engine, allowing for high-precision calculations, molecular structure validation, and thermodynamic modeling. By bridging the gap between natural language prompts and rigorous scientific computation, this skill ensures that all chemistry-related queries—from basic molecular weights to complex polymer analysis—are handled by validated, specialized algorithms rather than probabilistic language generation.

Installation

To integrate this skill, use the ClawHub command: clawhub install openclaw/skills/skills/gressling/paramus-chemistry. After installation, ensure you have set up your environment variables. The skill supports both local and cloud modes. For local execution (recommended for sensitive or proprietary research), download the Paramus tray application from https://cloud1.paramus.ai, which runs on port 8765. For cloud-based processing, set your PARAMUS_API_TOKEN environment variable using your credentials from the Paramus dashboard. Note that Windows users must use curl.exe instead of standard curl to ensure successful network communication.

Use Cases

This skill is ideal for medicinal chemists, materials scientists, and process engineers. Use it to calculate LogP and TPSA to assess drug-likeness, validate SMILES or InChI strings for chemical database entry, perform thermodynamic cycle analysis using CoolProp fluids, and run design-of-experiments (DOE) or PCA to optimize synthetic routes. Whether you are performing high-throughput screening or characterizing polymer properties, Paramus provides the necessary backend accuracy.

Example Prompts

1. "What is the molecular weight, LogP, and TPSA for the molecule with SMILES string C1=CC=C(C=C1)O?"
2. "Perform a thermodynamic analysis for water at 500K and 5MPa using CoolProp."
3. "Run a Principal Component Analysis on the following dataset of polymer refractive indices: [insert data here]."

Tips & Limitations

Always prioritize local mode (localhost:8765) when handling proprietary chemical structures to ensure your research remains private. If you must use cloud mode, be aware that your chemical data is transmitted to external servers. The skill is strictly for calculation; it does not replace expert human judgment in safety and laboratory synthesis protocols. Always double-check results if the provided input SMILES are non-standard or complex to avoid validation errors.